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Viagra FAQ:
What is Viagra®?
Viagra is a new drug developed
by Pfizer for the treatment of male
impotency. Its pharmacological
name is sildenafil citrate. It was
approved by the US Food
& Drug Administration in March 1998 for
the treatment of male impotency.
What does Viagra® do?
Viagra increases the body's
ability to achieve and maintain an erection
during sexual stimulation.
Viagra does not produce spontaneous
erections; sexual stimulus
must be present for erection to occur.
How does Viagra® work?
Viagra is dispensed as a
pill and ingested orally. After absorption into
the bloodstream, it functions
as an inhibitor to an enzyme called
phosphodiesterase 5 (PDE5)
which is found primarily in the penis. The
enzyme, PDE5 breaks down
cyclic GMP. Cyclic GMP is produced
during sexual stimulation,
leading to penis erection. The longer the
cyclic GMP is allowed to
persist, the greater the chance for increased
blood flow to the penis,
thereby generating an erection.
How long does Viagra® remain effective after ingestion?
The half-life is approximately
4 hours. If is recommended that sexual
stimulation commence from
30 to 60 minutes after Viagra is taken.
What happens if there
is no sexual stimulation
after Viagra® is
taken?
Sildenafil, or Viagra, is
excreted as metabolites from the body in feces
and urine.
What is Viagra®'s success rate?
Viagra's success rate is about 75%.
Are there any side effects?
Yes, a small percentage of
the study group experienced headaches,
nausea, facial flushing,
diarrhea, urinary tract infection and visual
changes to color sensitivity.
Who should NOT take Viagra?
The main contraindication
to prescribing Viagra® are people who
suffer from a rare disease,
retinitis pigmentosa, or those who are on
nitroglycerin or nitrous
oxide.
Recently, it has been reported
that 16 Viagra® patients have died.
While there is no direct
evidence that Viagra caused the deaths,
readers should be aware
that sexual activity increases cardiac risk.
Male impotence is often
a side effect of more serious cardiovascular
problems.
Viagra® MUST NOT be taken
by men who are on medications
containing nitrates, such
as nitroglycerine tablets, as this could lead to
dangerous lowering of blood
pressure. There is evidence to suggest
that Viagra may interact
with other medications in such a way as to
increase health risk. Men
who have medical conditions, such as sickle
cell anemia, leukemia, or
multiple myeloma, or those with
abnormally-shaped penis
should also not take Viagra because of a
possibility of producing
a sustained erection.
Can I get Viagra® over-the-counter?
No, Viagra® should only
be taken by prescription from a qualified
physician. You must tell
your doctor exactly what other medications
you are taking. FDA regulations
do not permit Viagra® to be
purchased without a physician's
prescription.
How often should Viagra be taken?
For those patients who have
been prescribed Viagra® by their doctors,
Viagra® should only
be taken once per day, about 1 hour before sexual
activity.
What Viagra® dosage is best?
Many physicians are now recommending
Viagra therapy begin with
25mg dosage, the minimum.
Standard dose is 50mg. Dosages higher
than 100mg per day are NOT
recommended.
Can Viagra® be combined
with other treatments for
erectile dysfunction?
The use of such combinations
is NOT recommended, since no studies
have been done to assess
its safety and effectiveness.
Are there concerns about
taking Viagra®
for long periods of time?
Yes. Some health practitioners
are concerned since little is known
about Viagra®'s long
term effects.
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